|
|
theophylline + NADPH + O2 + H+ <=> 3-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.178
methylxanthine N1-demethylase
|
–
|
MK
|
|
BRENDA:
BR50578
KEGG:
R07974
MetaCyc:
RXN-13108
|
|
|
|
theophylline + NADH + O2 + H+ <=> 3-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
K
|
|
BRENDA:
BR50578-a
KEGG:
R07973
MetaCyc:
RXN-13108_WOP
|
|
|
|
theophylline + NADH + O2 + H+ <=> 1-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
K
|
|
BRENDA:
BS412972
KEGG:
R07975
MetaCyc:
RXN-13110_WOP
|
|
|
|
Caffeine + O2 + NADPH + H+ <=> theophylline + formaldehyde + NADP+ + H2O
|
1.13.12
1.14.13.128
7-methylxanthine demethylase
|
–
–
|
K
|
|
BRENDA:
BS417831
KEGG:
R07972
|
|
|
|
theophylline + NADPH + O2 + H+ <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.179
methylxanthine N3-demethylase
|
–
|
MK
|
|
KEGG:
R07976
MetaCyc:
RXN-13110
|
|
|
|
Caffeine + NADH + H+ + O2 <=> theophylline + NAD+ + formaldehyde + H2O
|
1.13.12
|
–
|
K
|
|
KEGG:
R07971
|
|
|
|
xanthine + 2 S-adenosyl-L-methionine <=> theophylline + 2 S-adenosyl-L-homocysteine
|
not assigned
|
–
|
|
|
KEGG:
R08410
|
|
|
|
Caffeine + demethylated_methyl_donor <=> theophylline + alkane
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11544
|
|
|
|
theophylline + demethylated_methyl_donor <=> 3-Methylxanthine + alkane
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11545
|
|
|
|
theophylline <=> 1,3-dimethyluric_acid
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13113
|
|
|
|
theophylline + H2O + O2 <=> 1,3-dimethyluric_acid + H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
|
|
BRENDA:
BS375508
|
|
|
|
S-adenosyl-L-methionine + 3-Methylxanthine <=> S-adenosyl-L-homocysteine + theophylline
|
2.1.1.159
theobromine synthase
2.1.1.160
caffeine synthase
|
–
–
|
|
|
BRENDA:
BS385685
|
|
|
|
S-adenosyl-L-methionine + 1-Methylxanthine <=> S-adenosyl-L-homocysteine + theophylline
|
2.1.1.159
theobromine synthase
2.1.1.160
caffeine synthase
|
–
–
|
|
|
BRENDA:
BS385684
|
|
|
|
thymidine + theophylline <=> thymine + 2''-deoxytheophylline_riboside
|
2.4.2.6
nucleoside deoxyribosyltransferase
|
–
|
|
|
BRENDA:
BS354918
|
|
|
|
theophylline + 2 O2 + 2 NADH + 2 H+ <=> xanthine + 2 NAD+ + 2 H2O + 2 formaldehyde
|
1.14.13.128
7-methylxanthine demethylase
|
–
|
|
|
BRENDA:
BS412971
|
|